14 thg 12, 2017 - This uncommon condition, termed the neonatal small left colon syndrome (NSLCS), is characterized by an abrupt intestinal caliber transition at or near the splenic flexure and is associated, in approximately half of cases, with a maternal history of gestational diabetes mellitus. Neonatal small left colon syndrome is a functional disease of the lower colon which produces typical signs and symptoms of intestinal obstruction. . The etiology of the disease is unknown but it may relate to neurohumoral imbalances between the autonomic nervous system and glucagon. Neonatal small left colon syndrome is a cause of functional colon obstruction in newborn infants. Small left colon sydrome is subset of meconium plug syndrome in which an enema demonstrates an apparent transition zone between the dilated and the normal-to-decreased caliber distal colon at the splenic flexure. An unusually high incidence (40%) of maternal diabetes was observed in a series of 20 newborn infants who had low colonic obstruction and barium enema . 1 thg 11, 1999 - 1/4,000 to 1/8,00014. Absent anus, tight anus or fistula. Dilatation, surgery. Small left colon syndrome. Rare. Transition zone* at splenic flexure. Conditions that mimic this condition: Hirschsprung disease, cystic fibrosis, intestinal atresia, small left colon syndrome (seen in infants of mothers with diabetes), . Intestinal obstruction in the newborn infant and older child may be due to a variety of conditions, . meconium plug syndrome and neonatal small left colon syndrome . infancy and carries a very good prognosis after segmen- tal resection.60. Small Left Colon Anatomy Neonatal small left colon syndrome is a condition of func- tional immaturity of the large bowel in which the left colon is uniformly . 1 thg 9, 1999 - In small left colon syndrome, barium enema examination demonstrates mass with good through transmission due to clear fluid content or an .